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KMID : 0381219700020020041
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Journal of RIMSK
1970 Volume.2 No. 2 p.41 ~ p.44
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CORTICAL STEROIDS IN NEUROSURGERY
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Abstract
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The function of the adrenal cortex is controlled almost completely by adrenocorticotrophic hormone (ACTH) from the adenohypophysis. A variety of stimuli, such as all types of noxious stimuli, environmental changes and other types of stress, are mediated through the hypothalamus, where corticotropic releasing factor (CRF) is formed and through which travel´s the protal-venous system into the adenohypophysis.
The glucocorticoids influence the metabolism of carbohydrate, protein, fat, minerals and water. They also give the organism the capacity to resist all types of stimuli.
In neurosurgery, the administration of glucocorticoids has been advocated as a measure for pre and postoperative endocrine therapy for the surgery of the pituitary and surrounding areas; for preventing or reducing cerebral and spinal cord edema, and for certain types of infections, degenerative and demyelinization diseases.
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KEYWORD
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